ncRNA name | Miat |
ncRNA Category | lncRNA |
ID | 102552664 |
Ensembl | NA |
Synonyms | NA |
Disease name | diabetic retinopathy (DR) |
Species | Rattus norvegicus |
Tissues/Cell_line | rat retinal Müller cell line rMC-1 |
Methods | qPCR, Western blot, CHIP, transfection, MTT assay, flow cytometry, luciferase reporter assay |
Expression pattern | up-regulated |
Functional description | High glucose stimulation increased the cell apoptosis and decreased the cell activity, while MIAT suppression reversed the effect induced by high glucose, however, miR-29b knockdown reversed the effects induced by MIAT suppression. |
PubMed ID | 28246353 |
Year | 2017 |
Title | Long non-coding RNA MIAT acts as a biomarker in diabetic retinopathy by absorbing miR-29b and regulating cell apoptosis. |
Drug-related ncRNA | NO |
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